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26 March

Scientists Find Out Which Vitamin Kills Cancer Cells

Scientists Find Out Which Vitamin Kills Cancer Cells

Russian scientists have proved that vitamin B12 helps to kill cancer cells. They found out: to overcome oncological new growth, it is necessary to provoke oxidizing process in it, during which molecules will spoil proteins, lipids and even DNA of 'bad' cells.

Researchers noticed that by means of vitamin B12, it is possible to strengthen and accelerate this effect, reports a tvbrics.com correspondent with the reference to Biomolecules.

Researchers from the Institute of theoretical and experimental biophysics (ITEB) of RAS showed how it works. They mixed vitamin B12 with antineoplastic substance diethyldithiocarbamate (DDC). This pro-oxidizer filled cancer cells with aggressive oxidizing agents and thus provoked oxidizing stress in them. Despite all the malignancy, tumor cells began to perish as a new suicide program started in them.

Physicians found out that healthy and cancer cells die differently. One of such ways is so-called necroptosis. When it dies,a malignant cell brings many 'inconveniences' to others, provoking inflammation and further death of other cancer cells.

Apoptosis and autophagy is a less harsh form of cell destruction. Scientists often call these ways a ‘programmed suicide’. It is connected with the fact that a cell itself 'disconnects' all its vital functions, splitting itself. Both processes play a huge role in normal life of an organism saving it from old and damaged cells. Antitumor drugs are often madeon the assumption that they will turn on a 'suicide' program in cancer cells to make them die without disturbing cells around them. But some tumor cells get protection both against their own apoptosis, and against autophagy.

It turned out that vitamin B12 together with DDC can kill such cells, imbedding the third self-destruction program in them –paraptosis, which eventually brings cells to death.

Similar researches help the medical community develop drugfor cancer the rapy on the basis of combination of B12 and DDC.

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